MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

MagC, magnetic collection of ultrathin sections for volumetric correlative light and electron microscopy

Blog Article

The non-destructive collection of ultrathin sections on silicon wafers for post-embedding staining and volumetric correlative Toy light and electron microscopy traditionally requires exquisite manual skills and is tedious and unreliable.In MagC introduced here, sample blocks are augmented with a magnetic resin enabling the remote actuation and collection of hundreds of sections on wafer.MagC Hobby Paint allowed the correlative visualization of neuroanatomical tracers within their ultrastructural volumetric electron microscopy context.